Publikationen

Publikationen

Selected Publications

Zapiec, B., and Mombaerts, P. (2020). The zonal organization of odorant receptor gene choice in the main olfactory epithelium of the mouse. Cell Reports 30, 4220–4234. https://doi.org/10.1016/j.celrep.2020.02.110

 

Barnes, I.H.A., Ibarra-Soria, X., Fitzgerald, S., Gonzalez, J.M., Davidson, C., Hardy, P., Manthravadi, D., Van Gerven, L., Jorissen, M., Zeng, Z., Khan, M., Mombaerts, P., Harrow, J., Logan, D.W., and Frankish, A. (2020). Expert curation of the human and mouse olfactory receptor gene repertoires identifies conserved coding regions split across two exons. BMC Genomics 21, 196. https://doi.org/10.1186/s12864-020-6583-3

 

Bufe, B., Teuchert, Y., Schmid, A., Pyrski, M., Pérez-Gómez, A., Eisenbeis, J., Timm, T., Ishii, T., Lochnit, G., Bischoff, M., Mombaerts, P., Leinders-Zufall T., and Zufall, F. (2019). Bacterial MgrB peptide activates chemoreceptor Fpr3 in mouse accessory olfactory system and drives avoidance behaviour. Nat. Commun. 10, 4889. https://doi.org/10.1038/s41467-019-12842-x

 

Saraiva, L.R., Riveros-McKay, F., Mezzavilla, M., Abou-Moussa, E.H., Arayata, C.J., Makhlouf, M., Trimmer, C., Ibarra-Soria, X., Khan, M., Van Gerven, L., Jorissen, M., Gibbs, M., O’Flynn, C., McGrane, S., Mombaerts, P., Marioni, J.C., Mainland, J.D., and Logan D.W. (2019). A transcriptomic atlas of mammalian olfactory mucosae reveals an evolutionary influence on food odor detection in humans, Sci. Adv. 5. https://doi.org/10.1126/sciadv.aax0396

 

Zhou, H., Zeng, Z., Koentgen, F., Khan, M, and Mombaerts, P. (2019). The testicular soma of Tsc22d3 knockout mice supports spermatogenesis and germline transmission from spermatogonial stem cell lines upon transplantation. Genesis 5, e23295. https://doi.org/10.1002/dvg.23295

 

Torres-Torrelo, H., Ortega-Sáenz, P., Macías, D., Omura, M., Zhou, T., Matsunami, H., Johnson, R.S., Mombaerts, P., and López-Barneo, J. (2018). The role of Olfr78 in the breathing circuit of mice. Nature 561, E33-E40. DOI: https://doi.org/10.1038/s41586-018-0545-9

 

Akiyoshi, S., Ishii, T., Bai, Z., and Mombaerts, P. (2018). Subpopulations of vomeronasal sensory neurons with coordinated coexpression of type 2 vomeronasal receptor genes are differentially dependent on Vmn2r1. Eur. J. Neurosci. 47, 887-900. DOI: https://doi.org/10.1111/ejn.13875

 

Katidou, M., Grosmaitre, X., Lin, J., and Mombaerts, P. (2018). G-protein coupled receptors Mc4r and Drd1a can serve as surrogate odorant receptors in mouse olfactory sensory neurons. Mol. Cell Neurosci. 88, 138-147. DOI: https://doi.org/10.1016/j.mcn.2018.01.010.

 

Richter, K.N., Revelo, N.H., Seitz, K.J., Helm, M.S., Sarkar, D., Saleeb, R.S., D'Este, E., Eberle, J., Wagner, E., Vogl, C., Lazaro, D.F., Richter, F., Coy‐Vergara, J., Coceano, G., Boyden, E.S., Duncan, R.R., Hell, S.W., Lauterbach, M.A., Lehnart, S.E., Moser, T., Outeiro, T.F., Rehling, P., Schwappach, B., Testa, I., Zapiec, B., and Rizzoli, S.O. (2018). Glyoxal as an alternative fixative to formaldehyde in immunostaining and super‐resolution microscopy. EMBO J. 37, 139-159. DOI: https://doi.org/10.15252/embj.201695709

 

Zapiec, B., Dierks, B.V., Tan, S., Faull, R.L.M., Mombaerts, P., and Curtis, M.A. (2017). A ventral glomerular deficit in Parkinson’s disease revealed by whole olfactory bulb reconstruction. Brain 140, 2722-2736. DOI: https://doi.org/10.1093/brain/awx208

 

Lin, J., Khan, M., Zapiec, B., and Mombaerts, P. (2017). PDGFRA is not essential for the derivation and maintenance of mouse extraembryonic endoderm stem cell lines. Stem Cell Reports 9, 1062-1070. DOI: https://doi.org/10.1016/j.stemcr.2017.08.005

 

Low, V., and Mombaerts, P. (2017). Odorant receptor proteins in the mouse main olfactory epithelium and olfactory bulb. Neuroscience 344, 167-177. DOI: https://doi.org/10.1016/j.neuroscience.2016.12.044

 

Lin, J., Khan, M., Zapiec, B., and Mombaerts, P. (2016). Efficient derivation of extraembryonic endoderm stem cell lines from mouse postimplantation embryos. Sci. Rep. 6, 39457. DOI: https://doi.org/10.1038/srep39457

 

Bleymehl, K., Pérez-Gómez, A., Omura, M., Moreno-Pérez, A., Macias, D., Bai, Z., Johnson, R.S., Leinders-Zufall, T., Zufall, F., and Mombaerts, P. (2016), A sensor for low environmental oxygen in the mouse main olfactory epithelium. Neuron 92, 1196–1203; DOI: https://doi.org/10.1016/j.neuron.2016.11.001

 

Zapiec, B., Bressel, O.C., Khan, M., Walz, A., and Mombaerts, P. (2016). Neuropilin-1 and the positions of glomeruli in the mouse olfactory bulb. eneuro, ENEURO.0123-16.2016; DOI: https://doi.org/10.1523/ENEURO.0123-16.2016

 

Koentgen, F., Lin, J., Katidou, M., Chang, I., Khan, M., Watts, J. and Mombaerts, P. (2016). Exclusive transmission of the embryonic stem cell-derived genome through the mouse germline. genesis, 54: 326–333. DOI: https://doi.org/10.1002/dvg.22938

 

Bressel, O.C., Khan, M., and Mombaerts, P. (2016). Linear correlation between the number of olfactory sensory neurons expressing a given mouse odorant receptor gene and the total volume of the corresponding glomeruli in the olfactory bulb. J. Comp. Neurol. 524, 199-209. DOI: https://doi.org/10.1002/cne.23835

 

Tazir, B., Khan, M., Mombaerts, P., and Grosmaitre, X. (2016). The extremely broad odorant response profile of mouse olfactory sensory neurons expressing the odorant receptor MOR256-17 includes TAAR ligands. Eur. J. Neurosci., DOI: https://doi.org/10.1111/ejn.13153.

 

Saraiva, L.R., Ibarra-Soria, X., Khan, M., Omura, M., Scialdone, A., Mombaerts, P., Marioni, J.C., and Logan, D.W. (2015). Hierarchical deconstruction of mouse olfactory sensory neurons: from whole mucosa to single-cell RNA-seq. Sci. Rep. 5, 18178. DOI: https://doi.org/10.1038/srep18178

 

Zapiec, B., and Mombaerts, P. (2015). Multiplex assessment of the positions of odorant receptor-specific glomeruli in the mouse olfactory bulb by serial two-photon tomography. Proc. Natl. Acad. Sci. USA 112, E5873-5882. DOI: https://doi.org/10.1073/pnas.1512135112

 

Omura, M., and Mombaerts, P. (2015). Trpc2-expressing sensory neurons in the mouse main olfactory epithelium of type B express the soluble guanylate cyclase Gucy1b2. Mol. Cell. Neurosci. 65, 114-124. DOI: https://doi.org/10.1016/j.mcn.2015.02.012

 

Omura, M., and Mombaerts, P. (2014). Trpc2-expressing sensory neurons in the main olfactory epithelium of the mouse. Cell Rep. 8, 583-595.  DOI: https://doi.org/10.1016/j.celrep.2014.06.010

 

Leinders-Zufall, T., Ishii, T., Chamero, P., Hendrix, P., Oboti, L., Schmid, A., Kircher, S., Pyrski, M., Akiyoshi, S., Khan, M., Vaes, E., Zufall, F., and Mombaerts, P. (2014). A family of nonclassical class I MHC genes contributes to ultrasensitive chemodetection by mouse vomeronasal sensory neurons. J. Neurosci. 34, 5121-5133. DOI: https://doi.org/10.1523/JNEUROSCI.0186-14.2014

 

Omura, M., Grosmaitre, X., Ma, M., and Mombaerts, P. (2014). The beta2-adrenergic receptor as a surrogate odorant receptor in mouse olfactory sensory neurons. Mol. Cell. Neurosci. 58, 1-10. DOI: https://doi.org/10.1016/j.mcn.2013.10.010

 

Khan, M., Vaes, E., and Mombaerts, P. (2013). Temporal patterns of odorant receptor gene expression in adult and aged mice. Mol. Cell. Neurosci. 57, 120-129. DOI: https://doi.org/10.1016/j.mcn.2013.08.001

 

Lam, R.S., and Mombaerts, P. (2013). Odorant responsiveness of embryonic mouse olfactory sensory neurons expressing the odorant receptors S1 or MOR23. Eur. J. Neurosci. 38, 2210-2217. DOI: https://doi.org/10.1111/ejn.12240

 

Khan, M., Vaes, E., Mombaerts, P. (2011). Regulation of the probability of odorant receptor gene choice in mouse. Cell 147, 907-921. DOI: https://doi.org/10.1016/j.cell.2011.09.049

 

Leinders-Zufall, T., Ishii, T., Mombaerts, P., Zufall, F., and Boehm, T. (2009). Structural requirements for the activation of vomeronasal sensory neurons by MHC peptides. Nat. Neurosci. 12, 1551-1558. DOI: https://doi.org/10.1038/nn.2452

 

Grosmaitre, X., Fuss, S.H., Lee, A.C., Adipietro, K.A., Matsunami H., Mombaerts, P., and Ma, M. (2009). SR1, a mouse odorant receptor with an unusually broad response profile. J. Neurosci. 29, 14545-14552. DOI: https://doi.org/10.1523/JNEUROSCI.2752-09.2009

 

Bozza, T., Vassalli, A., Fuss, S., Zhang, J., Weiland, B., Pacifico, R., Feinstein, P., and Mombaerts, P. (2009). Mapping of class I and class II odorant receptors to glomerular domains by two distinct types of olfactory sensory neurons in the mouse. Neuron 61, 220-233. DOI: https://doi.org/10.1016/j.neuron.2008.11.010

 

Li, J., and Mombaerts, P. (2008). Nuclear transfer-mediated rescue of the nuclear genome of nonviable mouse cells frozen without cryoprotectant. Biol. Reprod. 79, 588-593.  DOI: https://doi.org/10.1095/biolreprod.108.069583

 

Ishii, T., and Mombaerts, P. (2008). Expression of non-classical class I major histocompatibility genes defines a tripartite organization of the mouse vomeronasal system. J. Neurosci. 28, 2332-2341. DOI: https://doi.org/10.1523/JNEUROSCI.4807-07.2008

 

Fuss, S.H., Omura, M., and Mombaerts, P. (2007). Local and cis effects of the H element on expression of odorant receptor genes in mouse. Cell 130, 373-384. DOI: https://doi.org/10.1016/j.cell.2007.06.023

 

Li, J., Greco, V., Guasch, G., Fuchs, E., and Mombaerts, P. (2007). Mice cloned from skin cells. Proc. Natl. Acad. Sci. USA 104, 2738-2743. DOI: https://doi.org/10.1073/pnas.0611358104

 

Hirota, J., Omura, M., and Mombaerts, P. (2007). Differential impact of Lhx2 deficiency on expression of class I and class II odorant receptor genes in mouse. Mol. Cell. Neurosci. 34, 679-688. DOI: https://doi.org/10.1016/j.cub.2005.09.010

 

Li, J., Ishii, T., Wen, D., and Mombaerts, P. (2005). Non-equivalence of cloned and clonal mice. Curr. Biol. 15, R756-757. DOI: https://doi.org/10.1016/j.cub.2005.09.010

 

Rothman, A., Feinstein, P., Hirota, J., and Mombaerts, P. (2005). The promoter of the mouse odorant receptor gene M71. Mol. Cell. Neurosci. 28, 535-546. DOI: https://doi.org/10.1016/j.mcn.2004.11.006

 

Feinstein, P., Bozza, T., Rodriguez, I., Vassalli, A., and Mombaerts, P. (2004). Axon guidance of mouse olfactory sensory neurons by odorant receptors and the β2 adrenergic receptor. Cell 117, 833-846. DOI: https://doi.org/10.1016/j.cell.2004.05.013

 

Feinstein, P., and Mombaerts, P. (2004). A contextual model for axonal sorting into glomeruli in the mouse olfactory system. Cell 117, 817-831. DOI: https://doi.org/10.1016/j.cell.2004.05.011

 

Li, J., Ishii, T., Feinstein, P., and Mombaerts, P. (2004). Odorant receptor gene choice is reset by nuclear transfer from mouse olfactory sensory neurons. Nature 428, 393-399. DOI: https://doi.org/10.1038/nature02433

 

Del Punta, K., Leinders-Zufall, T., Rodriguez, I., Jukam, D., Wysocki, C.J., Ogawa, S., Zufall, F., and Mombaerts, P. (2002). Deficient pheromone responses in mice lacking a cluster of vomeronasal receptor genes. Nature 419, 70-74. DOI: https://doi.org/10.1038/nature00955

 

Del Punta, K., Puche, A., Adams, N.C., Rodriguez, I., and Mombaerts, P. (2002). A divergent pattern of sensory axonal projections is rendered convergent by second-order neurons in the accessory olfactory bulb. Neuron 35, 1057-1066. DOI: https://doi.org/10.1016/s0896-6273(02)00904-2

 

Vassalli, A., Rothman, A., Feinstein, P., Zapotocky, M., and Mombaerts, P. (2002). Minigenes impart odorant receptor-specific axon guidance in the olfactory bulb. Neuron 35, 681-696. DOI: https://doi.org/10.1016/S0896-6273(02)00793-6

 

Bozza, T., Feinstein, P., Zheng, C., and Mombaerts, P. (2002). Odorant receptor expression defines functional units in the mouse olfactory system. J. Neurosci. 22, 3033-3043. DOI: https://doi.org/10.1523/JNEUROSCI.22-08-03033.2002

 

Rodriguez, I., Del Punta, K., Rothman, A., Ishii, T., and Mombaerts, P. (2002). Multiple new and isolated families within the mouse superfamily of V1r vomeronasal receptors. Nature Neurosci. 5, 134-139. DOI: https://doi.org/10.1038/nn795

 

Wakayama, T., Tabar, V., Rodriguez, I., Perry, A.C.F., Studer, L., and Mombaerts, P. (2001). Differentiation of embryonic stem cell lines generated from adult somatic cells by nuclear transfer. Science 292, 740-743. DOI: https://doi.org/10.1126/science.1059399

 

Wakayama, T., Rodriguez, I., Perry, A.C.F., Yanagimachi, R., and Mombaerts, P. (1999). Mice cloned from embryonic stem cells. Proc. Natl. Acad. Sci. USA 96, 14984-14989. DOI: https://doi.org/10.1073/pnas.96.26.14984

 

Rodriguez, I., Feinstein, P., and Mombaerts, P. (1999), Variable patterns of axonal projections of sensory neurons in the mouse vomeronasal system. Cell 97, 199-208. DOI: https://doi.org/10.1016/s0092-8674(00)80730-8

 
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